abstract：AIMS:Aldosterone activation is central to the sodium–fluid retention that marks the progression of heart failure (HF). The actions of dietary sodium restriction, a mainstay in HF management, on cardiorenal and neuroendocrine adaptations during the progression of HF are poorly understood. The study aim was to assess the...

journal_title：European journal of heart failure

authors： Miller WL,Borgeson DD,Grantham JA,Luchner A,Redfield MM,Burnett JC Jr

更新日期：2015-02-01 00:00:00

abstract：BACKGROUND:The use of oral anticoagulation in patients with heart failure in sinus rhythm remains controversial as previous large randomized controlled trials (RCTs) have not shown a survival benefit. However, heterogeneity exists among heart failure patients and it is possible that high-risk subgroups may benefit from...

journal_title：European journal of heart failure

authors： Goudie A,Elder D,Deshmukh H,Szwejkowski BR,Lang CC,George J

更新日期：2015-01-01 00:00:00

abstract：AIMS:The purpose of this study was to determine the prognostic significance and associated clinical profile of early post-discharge N-terminal pro-B-type natriuretic peptide (NT-proBNP) trajectory among patients hospitalized for worsening chronic heart failure (HHF). METHODS AND RESULTS:This post-hoc analysis of the A...

journal_title：European journal of heart failure

authors： Greene SJ,Maggioni AP,Fonarow GC,Solomon SD,Böhm M,Kandra A,Prescott MF,Reimund B,Hua TA,Lesogor A,Zannad F,Gheorghiade M,ASTRONAUT Investigators and Coordinators.

更新日期：2015-01-01 00:00:00

abstract：AIMS:As pulmonary arterial hypertension (PAH) is associated with significant morbidity and mortality, particularly among patients with right ventricular (RV) dysfunction, we aimed to determine the impact of therapy to reduce pulmonary vascular resistance (PVR) on RV and LV deformation in PAH. METHODS AND RESULTS:Right...

journal_title：European journal of heart failure

authors： Querejeta Roca G,Campbell P,Claggett B,Vazir A,Quinn D,Solomon SD,Shah AM

更新日期：2015-01-01 00:00:00

abstract：AIMS:Non-invasive measures of cardiac mechanical function may have the potential to serve as markers of risk for heart failure; however, limited data exist regarding clinical correlates and heritability of these measures in the community. METHODS AND RESULTS:We used speckle-tracking echocardiography to assess LV strai...

journal_title：European journal of heart failure

authors： Cheng S,McCabe EL,Larson MG,Chen MH,Osypiuk E,Lehman BT,Stantchev P,Aragam J,Solomon SD,Benjamin EJ,Vasan RS

更新日期：2015-01-01 00:00:00

abstract：AIMS:The true incidence of life-threatening ventricular tachyarrhythmic events and the risk of sudden cardiac death in the early stage of peripartum cardiomyopathy (PPCM) are still unknown. We aimed to assess the usefulness of the wearable cardioverter/defibrillator (WCD) to bridge a potential risk for life-threatening...

journal_title：European journal of heart failure

authors： Duncker D,Haghikia A,König T,Hohmann S,Gutleben KJ,Westenfeld R,Oswald H,Klein H,Bauersachs J,Hilfiker-Kleiner D,Veltmann C

更新日期：2014-12-01 00:00:00

abstract：AIMS:As periprocedural risk is low, MitraClip implantation is often performed in critically ill, not fully recompensated patients, who are in NYHA functional class IV at the time of the procedure, to accelerate convalescence. We herein sought to evaluate the procedural and 30-day outcome of this patient group. METHODS...

journal_title：European journal of heart failure

authors： Rudolph V,Huntgeburth M,von Bardeleben RS,Boekstegers P,Lubos E,Schillinger W,Ouarrak T,Eggebrecht H,Butter C,Plicht B,May A,Franzen O,Schofer J,Senges J,Baldus S

更新日期：2014-11-01 00:00:00

abstract：AIMS:Latent heart failure at rest can be observed in a number of patients upon exercise. Considering left atrial (LA) remodelling as the reflection of the cumulative effects of the LV filling pressure (FP) over time, our aim was to investigate whether the LA volume would predict abnormal exercise LVFP. METHODS AND RES...

journal_title：European journal of heart failure

authors： Hammoudi N,Achkar M,Laveau F,Boubrit L,Djebbar M,Allali Y,Komajda M,Isnard R

更新日期：2014-10-01 00:00:00

abstract：AIMS:Modulation of vagal tone using electrical vagal nerve stimulation or pharmacological acetylcholinesterase inhibition by donepezil exerts beneficial effects in an animal model of chronic heart failure (CHF). Considering different treatment mechanisms underlying renin-angiotensin system (RAS) suppression and parasym...

journal_title：European journal of heart failure

authors： Li M,Zheng C,Kawada T,Inagaki M,Uemura K,Sugimachi M

更新日期：2014-10-01 00:00:00

abstract：AIMS:Heart failure (HF) patients may be at risk of prescription of potentially inappropriate medicines (PIMs) yet no disease-specific list is available to assess PIM use in this population. A Consensus Potentially Inappropriate Medicines in Heart Failure (PIMHF) list was developed, assessed, and compared with an establ...

journal_title：European journal of heart failure

authors： Bermingham M,Ryder M,Travers B,Edwards N,Lalor L,Kelly D,Gallagher J,O'Hanlon R,McDonald K,Ledwidge M

更新日期：2014-08-01 00:00:00

abstract：AIMS:Beta-blockers (BBs) improve outcomes in heart failure. Results from the Cardiac Insufficiency Bisoprolol Study in Elderly (CIBIS-ELD) trial previously demonstrated the feasibility of heart rate, not maximum dose, as a treatment goal. In this pre-specified analysis, we investigated the prognostic value of achieved ...

journal_title：European journal of heart failure

authors： Düngen HD,Musial-Bright L,Inkrot S,Apostolović S,Edelmann F,Lainščak M,Sekularac N,Störk S,Tahirovic E,Tscholl V,Krackhardt F,Loncar G,Trippel TD,Gelbrich G

更新日期：2014-08-01 00:00:00

abstract：AIMS:To determine the impact of internationally recognized criteria for the diagnosis of heart failure with preserved ejection fraction (HF-PEF) on the feasibility of recruitment into a HF-PEF trial. METHODS AND RESULTS:We reviewed the medical records of 5883 consecutive patients admitted with heart failure across eig...

journal_title：European journal of heart failure

authors： Patel HC,Hayward C,di Mario C,Cowie MR,Lyon AR,Rosen SD

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND:Heart failure with preserved or mildly reduced ejection fraction (HFpEF) is common and, to date, therapeutic options are limited. Increased left atrial pressure is a key contributor to the symptoms associated with HFpEF, particularly during physical activity. We report the 30-day outcome of patients treated ...

journal_title：European journal of heart failure

authors： Søndergaard L,Reddy V,Kaye D,Malek F,Walton A,Mates M,Franzen O,Neuzil P,Ihlemann N,Gustafsson F

更新日期：2014-07-01 00:00:00

abstract：AIMS:The aim of this review is to assess the effects of exercise training on the symptoms of depression in heart failure (HF) patients. METHODS AND RESULTS:Randomized controlled trials of exercise training in patients with HF and symptoms of depression were identified. The depression data were pooled using meta-analys...

journal_title：European journal of heart failure

authors： Tu RH,Zeng ZY,Zhong GQ,Wu WF,Lu YJ,Bo ZD,He Y,Huang WQ,Yao LM

更新日期：2014-07-01 00:00:00

abstract：AIMS:Monitoring early signs of clinical deterioration could allow physicians to adjust medical treatment for patients at risk of acute heart failure decompensation. To date, several strategies using different surrogate measures of clinical status emerged, but none has yet been proven to predict clinical events. We hypo...

journal_title：European journal of heart failure

authors： Auricchio A,Gold MR,Brugada J,Nölker G,Arunasalam S,Leclercq C,Defaye P,Calò L,Baumann O,Leyva F

更新日期：2014-06-01 00:00:00

abstract：BACKGROUND:The EURObservational Research Programme is a rolling programme of cardiovascular registries and surveys of the European Society of Cardiology (ESC). These registries will provide information on the nature of cardiovascular disease and its management. This manuscript provides an update on new literature on pe...

journal_title：European journal of heart failure

authors： Sliwa K,Hilfiker-Kleiner D,Mebazaa A,Petrie MC,Maggioni AP,Regitz-Zagrosek V,Schaufelberger M,Tavazzi L,van Veldhuisen DJ,Roos-Hesslink JW,Shah AJ,Seferovic PM,Elkayam U,van Spaendonck-Zwarts K,Bachelier-Walenta K,Mouquet F

更新日期：2014-05-01 00:00:00

abstract：AIMS:Scarce data are available on the effect of the traditional Mediterranean diet (TMD) on heart failure biomarkers. We assessed the effect of TMD on biomarkers related to heart failure in a high cardiovascular disease risk population. METHODS AND RESULTS:A total of 930 subjects at high cardiovascular risk (420 men a...

journal_title：European journal of heart failure

authors： Fitó M,Estruch R,Salas-Salvadó J,Martínez-Gonzalez MA,Arós F,Vila J,Corella D,Díaz O,Sáez G,de la Torre R,Mitjavila MT,Muñoz MA,Lamuela-Raventós RM,Ruiz-Gutierrez V,Fiol M,Gómez-Gracia E,Lapetra J,Ros E,Serra-Majem L

更新日期：2014-05-01 00:00:00

abstract：AIMS:Women are more likely to develop heart failure with preserved ejection fraction (HFpEF) than men. We studied the relationship between sex and cardiovascular structure and function in patients with HFpEF. METHODS AND RESULTS:The study included 279 participants from the PARAMOUNT study (57% women) with analysable b...

journal_title：European journal of heart failure

authors： Gori M,Lam CS,Gupta DK,Santos AB,Cheng S,Shah AM,Claggett B,Zile MR,Kraigher-Krainer E,Pieske B,Voors AA,Packer M,Bransford T,Lefkowitz M,McMurray JJ,Solomon SD,PARAMOUNT Investigators.

更新日期：2014-05-01 00:00:00

abstract：AIMS:ACE-inhibitors, β-blockers, implantable cardioverter-defibrillator (ICD) and cardiac resynchronization therapy (CRT) improved prognosis of heart failure. We sought to analyse the long-term prognostic impact of evidence-based integrated therapeutic strategies in patients with idiopathic dilated cardiomyopathy (IDCM...

journal_title：European journal of heart failure

authors： Merlo M,Pivetta A,Pinamonti B,Stolfo D,Zecchin M,Barbati G,Di Lenarda A,Sinagra G

更新日期：2014-03-01 00:00:00

abstract：AIMS:The cardio-renal syndrome plays a critical role in acute heart failure (HF). Levosimendan, an inodilator drug, has a positive but controversial effect on kidney. Our aim was to evaluate its effects on both renal and systemic haemodynamic parameters as well as on renal function, explaining the possible mechanisms i...

journal_title：European journal of heart failure

authors： Fedele F,Bruno N,Brasolin B,Caira C,D'Ambrosi A,Mancone M

更新日期：2014-03-01 00:00:00

abstract：:Heart rate not only predicts outcome but may also be a therapeutic target in patients with chronic heart failure. Several classes of pharmacological agents can be used to modulate heart rate, including beta-blockers, ivabradine, digoxin, amiodarone, and verapamil. Choice of agent will depend on heart rhythm, co-morbid...

journal_title：European journal of heart failure

authors： Dobre D,Borer JS,Fox K,Swedberg K,Adams KF,Cleland JG,Cohen-Solal A,Gheorghiade M,Gueyffier F,O'Connor CM,Fiuzat M,Patak A,Piña IL,Rosano G,Sabbah HN,Tavazzi L,Zannad F

更新日期：2014-01-01 00:00:00

abstract：AIMS:Risk stratification in patients admitted with worsening heart failure (HF) is essential for tailoring therapy and counselling. Risk models are available but rarely used, in part because many require laboratory and imaging results that are not routinely available. Body temperature is associated with prognosis in ot...

journal_title：European journal of heart failure

authors： Payvar S,Spertus JA,Miller AB,Casscells SW,Pang PS,Zannad F,Swedberg K,Maggioni AP,Reid KJ,Gheorghiade M,Efficacy of Vasopressin Antagonism in Heart Failure Outcome Study with Tolvaptan (EVEREST) Investigators.

更新日期：2013-12-01 00:00:00

abstract：AIMS:Post-discharge morbidity and mortality for acute heart failure (AHF) patients remains high. Although the adverse effects of neurohormonal activation are well known in chronic HF, the prognostic significance of serum aldosterone in patients hospitalized for AHF has not been well studied. METHODS AND RESULTS:A seco...

journal_title：European journal of heart failure

authors： Girerd N,Pang PS,Swedberg K,Fought A,Kwasny MJ,Subacius H,Konstam MA,Maggioni A,Gheorghiade M,Zannad F,EVEREST investigators.

更新日期：2013-11-01 00:00:00

abstract：AIMS:Knowledge of patient preferences is vital for delivering optimal healthcare. This study uses utility measurement to assess the preferences of heart failure (HF) patients regarding quality of life or longevity. The utility approach represents the perspective of a patient; facilitates the combination of mortality, m...

journal_title：European journal of heart failure

authors： Kraai IH,Vermeulen KM,Luttik ML,Hoekstra T,Jaarsma T,Hillege HL

更新日期：2013-10-01 00:00:00

abstract：AIMS:Galectin-3 is a prognostic heart failure (HF) biomarker that may mediate cardiac fibrosis. We examined the value of serial galectin-3 measurement for prognosis and response to therapy in chronic HF. METHODS AND RESULTS:A total of 151 subjects with LV systolic dysfunction (LVSD) were followed through 908 visits ov...

journal_title：European journal of heart failure

authors： Motiwala SR,Szymonifka J,Belcher A,Weiner RB,Baggish AL,Sluss P,Gaggin HK,Bhardwaj A,Januzzi JL

更新日期：2013-10-01 00:00:00

abstract：:Anti-beta-1-adrenergic receptor antibodies (anti-β1AR Abs) have long been implicated in the pathogenesis of dilated cardiomyopathy (DCM). It is believed that these autoantibodies bind to and constitutively stimulate the β1AR to promote pathological cardiac remodelling and β1AR desensitization and downregulation. The p...

journal_title：European journal of heart failure

authors： Patel PA,Hernandez AF

更新日期：2013-07-01 00:00:00

abstract：AIMS:Recent studies have shown that microRNAs (miRNAs), besides being potent regulators of gene expression, can additionally serve as circulating biomarkers of disease. The aim of this study is to determine if plasma miRNAs can be used as indicators of disease progression or therapeutic efficacy in hypertension-induced...

journal_title：European journal of heart failure

authors： Dickinson BA,Semus HM,Montgomery RL,Stack C,Latimer PA,Lewton SM,Lynch JM,Hullinger TG,Seto AG,van Rooij E

更新日期：2013-06-01 00:00:00

abstract：AIMS:To investigate the relationship between decongestion, central venous pressure, and risk of worsening renal function (WRF) in patients with acute decompensated heart failure (ADHF). METHODS AND RESULTS:We studied 475 patients with ADHF, of whom 238 underwent right heart catheterization. Right atrial pressure (RAP)...

journal_title：European journal of heart failure

authors： Aronson D,Abassi Z,Allon E,Burger AJ

更新日期：2013-06-01 00:00:00

abstract：AIMS:The proteasome prevents the intracellular accumulation of proteins and its impairment can lead to structural and functional alterations, as noted for the coronary vasculature in a previous study. Utilizing the same model, this study was designed to test the hypothesis that chronic proteasome inhibition (PSI) also ...

journal_title：European journal of heart failure

authors： Herrmann J,Wohlert C,Saguner AM,Flores A,Nesbitt LL,Chade A,Lerman LO,Lerman A

更新日期：2013-06-01 00:00:00

abstract：AIMS:The objective of this study was to establish the acute effects of hypoxia on clinical, spirometric, haemodynamic, and echocardiographic variables. Reducing inspired oxygen to 15%, as experienced during commercial air travel, decreases arterial oxygen saturation, increases respiratory rate and pulmonary artery pres...

journal_title：European journal of heart failure

authors： Hobkirk JP,Damy T,Walters M,Bennett A,Smith SJ,Ingle L,Clark AL,Cleland JG

更新日期：2013-05-01 00:00:00

abstract：AIMS:In the Digitalis Investigation Group (DIG) trial, digoxin reduced mortality or hospitalization due to heart failure (HF) in several pre-specified high-risk subgroups of HF patients, but data on protocol-specified 2-year outcomes were not presented. In the current study, we examined the effect of digoxin on HF deat...

journal_title：European journal of heart failure

authors： Gheorghiade M,Patel K,Filippatos G,Anker SD,van Veldhuisen DJ,Cleland JG,Metra M,Aban IB,Greene SJ,Adams KF,McMurray JJ,Ahmed A

更新日期：2013-05-01 00:00:00

abstract：AIMS:Mutations in the lamin A/C gene (LMNA) cause a variety of clinical phenotypes, including dilated cardiomyopathy. LMNA is one of the most prevalent mutated genes in dilated cardiomyopathy, and is associated with a high risk of arrhythmias, sudden cardiac death, and heart failure. There are few data on the impact of...

journal_title：European journal of heart failure

authors： van Rijsingen IA,Nannenberg EA,Arbustini E,Elliott PM,Mogensen J,Hermans-van Ast JF,van der Kooi AJ,van Tintelen JP,van den Berg MP,Grasso M,Serio A,Jenkins S,Rowland C,Richard P,Wilde AA,Perrot A,Pankuweit S,Zwinderman

更新日期：2013-04-01 00:00:00

abstract：AIMS:Structural abnormalities causing cardiac deterioration in hypertensive heart disease (HHD) are poorly understood. The aim of the study was to evaluate left ventricular (LV) myocardial changes in patients with HHD and cardiac failure. METHODS AND RESULTS:Among 1229 patients undergoing an LV or biventricular endomy...

journal_title：European journal of heart failure

authors： Frustaci A,Francone M,Petrosillo N,Chimenti C

更新日期：2013-03-01 00:00:00

abstract：AIM:Heart failure (HF) is a common condition with which high mortality, morbidity, and poor quality of life are associated. It has previously been shown that use of HF management programmes (HFMPs) in HF clinics can be beneficial. The purpose of this study was to evaluate if the use of HFMPs also has beneficial effects...

journal_title：European journal of heart failure

authors： Agvall B,Alehagen U,Dahlström U

更新日期：2013-02-01 00:00:00

abstract：AIMS:To investigate the prognostic value of autonomic variables in patients with symptomatic chronic heart failure (HF) treated according to current recommendations. METHODS AND RESULTS:We analysed 24 h time-domain [standard deviation of all normal-to-normal RR intervals (SDNN)], frequency-domain [very low frequency a...

journal_title：European journal of heart failure

authors： La Rovere MT,Pinna GD,Maestri R,Barlera S,Bernardinangeli M,Veniani M,Nicolosi GL,Marchioli R,Tavazzi L,GISSI-HF Investigators.

更新日期：2012-12-01 00:00:00

abstract：AIM:The exercise Doppler echocardiographic stress test can be of interest in the management of asymptomatic patients with primary mitral regurgitation (MR). The resting brain natriuretic peptide (BNP) level is a good surrogate marker of the consequences of MR and is a powerful predictor of outcome. The incremental prog...

journal_title：European journal of heart failure

authors： Magne J,Mahjoub H,Pibarot P,Pirlet C,Pierard LA,Lancellotti P

更新日期：2012-11-01 00:00:00

abstract：AIMS:Quantification of linear lung ultrasound (LUS) artefacts (B-lines) represents a novel, non-invasive approach to assess pulmonary congestion. We investigated the relationship between the number of B-lines (vertical artefacts arising from the pleural line) and intracardiac pressures. METHODS AND RESULTS:Prior to sc...

journal_title：European journal of heart failure

authors： Platz E,Lattanzi A,Agbo C,Takeuchi M,Resnic FS,Solomon SD,Desai AS

更新日期：2012-11-01 00:00:00

abstract：UNLABELLED:Aim Frequent ventricular premature contractions (VPCs) may cause haemodynamic deterioration and reversible left ventricular (LV) dysfunction. We aimed to clarify this mechanism. METHODS AND RESULTS:The haemodynamics, echocardiographic parameters, and plasma brain natriuretic peptide (BNP) level were assesse...

journal_title：European journal of heart failure

authors： Kuroki K,Tada H,Seo Y,Ishizu T,Igawa M,Yamasaki H,Igarashi M,Machino T,Naruse Y,Sekiguchi Y,Murakoshi N,Aonuma K

更新日期：2012-10-01 00:00:00

abstract：AIMS:Congestive heart failure (CHF) is associated with impaired renal function. Previously, we have demonstrated that rats with decompensated CHF exhibited exaggerated sensitivity to the adverse renal effects of increased increased intra-abdominal pressure (IAP) as compared with normal controls. This study tested wheth...

journal_title：European journal of heart failure

authors： Bishara B,Abu-Saleh N,Awad H,Ghrayeb N,Goltsman I,Aronson D,Khamaysi I,Assady S,Armaly Z,Haddad S,Haddad E,Abassi Z

更新日期：2012-10-01 00:00:00

abstract：AIMS:Reliable detectors of worsening renal function (WRF) in Emergency Department (ED) patients with acute heart failure (AHF) are limited. We hypothesized that initial urinary neutrophil gelatinase-associated lipocalcin (NGAL) levels, and changes in urinary NGAL levels after initial ED AHF therapy, would be associated...

journal_title：European journal of heart failure

authors： Collins SP,Hart KW,Lindsell CJ,Fermann GJ,Weintraub NL,Miller KF,Roll SN,Sperling MI,Sawyer DB,Storrow AB

更新日期：2012-09-01 00:00:00